Citation: NI Ya-Ru, LIN Qing, DONG Ya, LU Chun-Hua, LAN Xiang-Hui, XU Zhong-Zi. In Vitro Bioactive Behaviors of Hydrated Tricalcium Silicate Paste in Different Simulated Body Fluids[J]. Chinese Journal of Inorganic Chemistry, ;2012, 28(12): 2548-2557. shu

In Vitro Bioactive Behaviors of Hydrated Tricalcium Silicate Paste in Different Simulated Body Fluids

NI Ya-Ru ^1,, ,
LIN Qing ² ,
DONG Ya ¹ ,
LU Chun-Hua ¹ ,
LAN Xiang-Hui ¹ ,
XU Zhong-Zi ^1,,

1.
1. State Key Laboratory of Materials-Orient Chemical Engineering, College of Materials Science and Engineering, Nanjing University of Technology, Nanjing 210009, China;

Corresponding author: NI Ya-Ru, XU Zhong-Zi,
Received Date: 20 December 2012
Available Online: 8 May 2012
Fund Project: 国家973计划(2009CB623105) (2009CB623105)南京市医学科技发展重点项目(ZKX07016) (ZKX07016)江苏省研究生创新基金项目(CX09B-127Z)资助项目. (CX09B-127Z)

The in vitro bioactive behaviors of hydrated tricalcium silicate(Ca₃SiO₅, C₃S) paste were studied. The results show that dry hydrated C₃S paste contains about 23.97wt% Ca(OH)₂, and the dissolution of Ca(OH)₂ results in increased pH value of simulated body fluid (SBF). Apatite particles are firstly induced to deposit on hydrated C₃S paste surface. Then, hydrated C₃S paste surface is co-deposited with CaCO₃ and apatite particles. HCO₃^- is the principal buffer system of SBF, and the carbonation of Ca(OH)₂ and deposition of CaCO₃ mainly contribute to the decreasing of pH value. As a result of lower ion exchanges, hydrated C₃S paste surface is finally deposited with apatite. The deposition of apatite contributes to the further decreasing of pH value. The in vitro bioactivity and further biocompatibility evaluations of C₃S and C₃S devised materials must be improved by considering the concentration and behavior of HCO₃^- in living body.
- in vitro bioactivity;tricalcium silicate;apatite;calcium carbonate
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