Citation: NI Ya-Ru, LIN Qing, DONG Ya, LU Chun-Hua, LAN Xiang-Hui, XU Zhong-Zi. In Vitro Bioactive Behaviors of Hydrated Tricalcium Silicate Paste in Different Simulated Body Fluids[J]. Chinese Journal of Inorganic Chemistry, ;2012, 28(12): 2548-2557.
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The in vitro bioactive behaviors of hydrated tricalcium silicate(Ca3SiO5, C3S) paste were studied. The results show that dry hydrated C3S paste contains about 23.97wt% Ca(OH)2, and the dissolution of Ca(OH)2 results in increased pH value of simulated body fluid (SBF). Apatite particles are firstly induced to deposit on hydrated C3S paste surface. Then, hydrated C3S paste surface is co-deposited with CaCO3 and apatite particles. HCO3- is the principal buffer system of SBF, and the carbonation of Ca(OH)2 and deposition of CaCO3 mainly contribute to the decreasing of pH value. As a result of lower ion exchanges, hydrated C3S paste surface is finally deposited with apatite. The deposition of apatite contributes to the further decreasing of pH value. The in vitro bioactivity and further biocompatibility evaluations of C3S and C3S devised materials must be improved by considering the concentration and behavior of HCO3- in living body.
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