Citation: Xiong Lin, Fan Yong, Zhang Fan. Research Progress on Rare Earth Nanocrystals for In Vivo Imaging and Sensing in Near Infrared Region[J]. Acta Chimica Sinica, ;2019, 77(12): 1239-1249. doi: 10.6023/A19080305 shu

Research Progress on Rare Earth Nanocrystals for In Vivo Imaging and Sensing in Near Infrared Region

State Key Laboratory of Molecular Engineering of Polymers, Department of Chemistry, Fudan University, Shanghai 200433

Corresponding author: Zhang Fan, zhang_fan@fudan.edu.cn
Received Date: 16 August 2019
Available Online: 18 December 2019
Fund Project: the National Key R & D Program of China 2017YFA0207303Project supported by National Science Fund for Distinguished Young Scholars (No. 21725502), the National Key R & D Program of China (No. 2017YFA0207303), the Key Basic Research Program of Science and Technology Commission of Shanghai Municipality (No. 17JC1400100)National Science Fund for Distinguished Young Scholars 21725502the Key Basic Research Program of Science and Technology Commission of Shanghai Municipality 17JC1400100

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In vivo imaging and sensing play a critical role in modern biological and medical research. Compared with other techniques such as computed tomography (CT), positron emission tomography (PET) and nuclear magnetic resonance (NMR), fluorescence imaging and analysis are featured by fast feedback, high sensitivity, and high spatiotemporal resolution. Especially, the application of near infrared (NIR) light as both excitation and emission signals provides increased tissue penetration and improved imaging quality and sensitivity due to reduced light scattering and auto-fluorescence. Among various materials investigated for in vivo imaging and bio-sensing, lanthanide-based nanocrystals display rich excitation/emission wavelengths in the NIR range, good photo and chemical stability, large Stokes shifts. In recent years, the research on lanthanide-based nanocrystals for in vivo imaging and sensing has seen rapid progress. Through nanoscale material design and synthesis, it is possible to fine tune the optical properties of lanthanide-based nanocrystals. By properly choosing different lanthanide ions as activators and sensitizers, multiple excitation/emission wavelengths can be obtained. The careful design of core-shell structure of nanocrystals enables improved fluorescence efficiency and tailorable fluorescence life time through controlled energy transfer. On the other side, the surface of lanthanide-based nanocrystals can be modified through coating, absorption or ligand exchange to enhance the biocompatibility, targeting capability, and bio-responsiveness. Taking advantage of this high flexibility and versatility, there are great opportunities for these lanthanide-based nanocrystals in various in vivo imaging and sensing applications. This review first outlines the general technique requirements for in vivo imaging and sensing. Then, the composition, synthesis and basic properties of lanthanide-based nanocrystals are briefly introduced. Subsequently, the routes for tailoring the optical and biochemical properties of lanthanide-based nanocrystals are discussed in detail, with an emphasis on the material designs and surface modifications for in vivo imaging and analysis. It is expected that this work will inspire new ideas for accelerating the clinic translation of rare earth nanocrystals-based imaging and sensing techniques.
- rare earth nanocrystals,
- bio-imaging,
- bio-sensing,
- near infrared,
- fluorescence
1. [1]
  Antaris, A. L.; Chen, H.; Cheng, K.; Sun, Y.; Hong, G.; Qu, C.; Diao, S.; Deng, Z.; Hu, X.; Zhang, B.; Zhang, X.; Yaghi, O. K.; Alamparambil, Z. R.; Hong, X.; Cheng, Z.; Dai, H. Nat. Mater. 2015, 15, 235.
2. [2]
  Hou, J.; Li, K.; Qin, C.; Yu, X. Chin. J. Org. Chem. 2018, 38, 612.
3. [3]
  Vijayaraghavan, P.; Liu, C.-H.; Vankayala, R.; Chiang, C.-S.; Hwang, K. C. Adv. Mater. 2014, 26, 6689. doi: 10.1002/adma.201400703
4. [4]
  Zhang, Y.; Wu, M.; Wu, M.; Guo, L.; Cao, L.; Wu, H.; Zhang, X. Acta Chim. Sinica 2018, 76, 709.
5. [5]
  Li, D.; Jing, P.; Sun, L.; An, Y.; Shan, X.; Lu, X.; Zhou, D.; Han, D.; Shen, D.; Zhai, Y.; Qu, S.; Zbořil, R.; Rogach, A. L. Adv. Mater. 2018, 30, 1705913. doi: 10.1002/adma.201705913
6. [6]
  Welsher, K.; Sherlock, S. P.; Dai, H. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 8943. doi: 10.1073/pnas.1014501108
7. [7]
  Li, C.; Zhang, Y.; Wang, M.; Zhang, Y.; Chen, G.; Li, L.; Wu, D.; Wang, Q. Biomaterials 2014, 35, 393. doi: 10.1016/j.biomaterials.2013.10.010
8. [8]
  Xu, Y.; Zhao, Y.; Zhang, Y.; Cui, Z.; Wang, L.; Fan, C.; Gao, J.; Sun, Y. Acta Chim. Sinica 2018, 76, 393.
9. [9]
  Hong, G.; Zou, Y.; Antaris, A. L.; Diao, S.; Wu, D.; Cheng, K.; Zhang, X.; Chen, C.; Liu, B.; He, Y.; Wu, J. Z.; Yuan, J.; Zhang, B.; Tao, Z.; Fukunaga, C.; Dai, H. Nat. Commun. 2014, 5, 4206. doi: 10.1038/ncomms5206
10. [10]
  Naczynski, D. J.; Tan, M. C.; Zevon, M.; Wall, B.; Kohl, J.; Kulesa, A.; Chen, S.; Roth, C. M.; Riman, R. E.; Moghe, P. V. Nat. Commun. 2013, 4, 2199. doi: 10.1038/ncomms3199
11. [11]
  Chen, G.; Qiu, H.; Prasad, P. N.; Chen, X. Chem. Rev. 2014, 114, 5161. doi: 10.1021/cr400425h
12. [12]
  Bünzli, J.-C. G. Chem. Rev. 2010, 110, 2729. doi: 10.1021/cr900362e
13. [13]
  Gai, S.; Li, C.; Yang, P.; Lin, J. Chem. Rev. 2013, 114, 2343.
14. [14]
  Dong, H.; Du, S.-R.; Zheng, X.-Y.; Lyu, G.-M.; Sun, L.-D.; Li, L.-D.; Zhang, P.-Z.; Zhang, C.; Yan, C.-H. Chem. Rev. 2015, 115, 10725. doi: 10.1021/acs.chemrev.5b00091
15. [15]
  Dang, X.; Gu, L.; Qi, J.; Correa, S.; Zhang, G.; Belcher, A. M.; Hammond, P. T. Proc. Natl. Acad. Sci. U. S. A. 2016, 113, 5179. doi: 10.1073/pnas.1521175113
16. [16]
  Li, X.; Zhang, F.; Zhao, D. Chem. Soc. Rev. 2015, 44, 1346. doi: 10.1039/C4CS00163J
17. [17]
  Xu, J.; Gulzar, A.; Yang, P.; Bi, H.; Yang, D.; Gai, S.; He, F.; Lin, J.; Xing, B.; Jin, D. Coord. Chem. Rev. 2019, 381, 104. doi: 10.1016/j.ccr.2018.11.014
18. [18]
  Ma, P. a.; Xiao, H.; Li, X.; Li, C.; Dai, Y.; Cheng, Z.; Jing, X.; Lin, J. Adv. Mater. 2013, 25, 4898. doi: 10.1002/adma.201301713
19. [19]
  Dai, Y.; Xiao, H.; Liu, J.; Yuan, Q.; Ma, P. A.; Yang, D.; Li, C.; Cheng, Z.; Hou, Z.; Yang, P.; Lin, J. J. Am. Chem. Soc. 2013, 135, 18920. doi: 10.1021/ja410028q
20. [20]
  Zhou, L.; Wang, R.; Yao, C.; Li, X.; Wang, C.; Zhang, X.; Xu, C.; Zeng, A.; Zhao, D.; Zhang, F. Nat. Commun. 2015, 6, 6938. doi: 10.1038/ncomms7938
21. [21]
  Wang, R.; Zhang, F. J. Mater. Chem. B 2014, 2, 2422. doi: 10.1039/c3tb21447h
22. [22]
  Li, X.; Shen, D.; Yang, J.; Yao, C.; Che, R.; Zhang, F.; Zhao, D. Chem. Mater. 2013, 25, 106. doi: 10.1021/cm3033498
23. [23]
  Liu, L.; Li, X.; Fan, Y.; Wang, C.; El-Toni, A. M.; Alhoshan, M. S.; Zhao, D.; Zhang, F. Chem. Mater. 2019, 31, 5608. doi: 10.1021/acs.chemmater.9b01348
24. [24]
  Fan, Y.; Liu, L.; Zhang, F. Nano Today 2019, 25, 68. doi: 10.1016/j.nantod.2019.02.009
25. [25]
  Wang, F.; Liu, X. J. Am. Chem. Soc. 2008, 130, 5642. doi: 10.1021/ja800868a
26. [26]
  Zhao, J.; Jin, D.; Schartner, E. P.; Lu, Y.; Liu, Y.; Zvyagin, A. V.; Zhang, L.; Dawes, J. M.; Xi, P.; Piper, J. A.; Goldys, E. M.; Monro, T. M. Nat. Nanotechnol. 2013, 8, 729. doi: 10.1038/nnano.2013.171
27. [27]
  Wang, F.; Deng, R.; Wang, J.; Wang, Q.; Han, Y.; Zhu, H.; Chen, X.; Liu, X. Nat. Mater. 2011, 10, 968. doi: 10.1038/nmat3149
28. [28]
  Garfield, D. J.; Borys, N. J.; Hamed, S. M.; Torquato, N. A.; Tajon, C. A.; Tian, B.; Shevitski, B.; Barnard, E. S.; Suh, Y. D.; Aloni, S.; Neaton, J. B.; Chan, E. M.; Cohen, B. E.; Schuck, P. J. Nat. Photonics 2018, 12, 402. doi: 10.1038/s41566-018-0156-x
29. [29]
  Wei, W.; Chen, G.; Baev, A.; He, G. S.; Shao, W.; Damasco, J.; Prasad, P. N. J. Am. Chem. Soc. 2016, 138, 15130. doi: 10.1021/jacs.6b09474
30. [30]
  Schietinger, S.; Aichele, T.; Wang, H.-Q.; Nann, T.; Benson, O. Nano Lett. 2010, 10, 134. doi: 10.1021/nl903046r
31. [31]
  Xu, W.; Lee, T. K.; Moon, B. S.; Song, H. W.; Chen, X.; Chun, B.; Kim, Y. J.; Kwak, S. K.; Chen, P.; Kim, D. H. Adv. Opt. Mater. 2018, 6, 1701119. doi: 10.1002/adom.201701119
32. [32]
  Huang, B.; Sun, M.; Dougherty, A. W.; Dong, H.; Xu, Y.-J.; Sun, L.-D.; Yan, C.-H. Nanoscale 2017, 9, 18490. doi: 10.1039/C7NR06729A
33. [33]
  Zou, W.; Visser, C.; Maduro, J. A.; Pshenichnikov, M. S.; Hummelen, J. C. Nat. Photonics 2012, 6, 560. doi: 10.1038/nphoton.2012.158
34. [34]
  Wang, Y.-F.; Liu, G.-Y.; Sun, L.-D.; Xiao, J.-W.; Zhou, J.-C.; Yan, C.-H. ACS Nano 2013, 7, 7200. doi: 10.1021/nn402601d
35. [35]
  Xie, X.; Gao, N.; Deng, R.; Sun, Q.; Xu, Q.-H.; Liu, X. J. Am. Chem. Soc. 2013, 135, 12608. doi: 10.1021/ja4075002
36. [36]
  Li, X.; Wang, R.; Zhang, F.; Zhou, L.; Shen, D.; Yao, C.; Zhao, D. Sci. Rep. 2013, 3, 3536. doi: 10.1038/srep03536
37. [37]
  Shen, J.; Chen, G.; Vu, A.-M.; Fan, W.; Bilsel, O. S.; Chang, C.-C.; Han, G. Adv. Opt. Mater. 2013, 1, 644. doi: 10.1002/adom.201300160
38. [38]
  Zhong, Y.; Tian, G.; Gu, Z.; Yang, Y.; Gu, L.; Zhao, Y.; Ma, Y.; Yao, J. Adv. Mater. 2014, 26, 2831. doi: 10.1002/adma.201304903
39. [39]
  Wang, D.; Xue, B.; Kong, X.; Tu, L.; Liu, X.; Zhang, Y.; Chang, Y.; Luo, Y.; Zhao, H.; Zhang, H. Nanoscale 2015, 7, 190. doi: 10.1039/C4NR04953E
40. [40]
  Cheng, X.; Pan, Y.; Yuan, Z.; Wang, X.; Su, W.; Yin, L.; Xie, X.; Huang, L. Adv. Funct. Mater. 2018, 28, 1800208. doi: 10.1002/adfm.201800208
41. [41]
  Liu, L.; Wang, S.; Zhao, B.; Pei, P.; Fan, Y.; Li, X.; Zhang, F. Angew. Chem., Int. Ed. 2018, 57, 7518. doi: 10.1002/anie.201802889
42. [42]
  Chen, Q.; Xie, X.; Huang, B.; Liang, L.; Han, S.; Yi, Z.; Wang, Y.; Li, Y.; Fan, D.; Huang, L.; Liu, X. Angew. Chem., Int. Ed. 2017, 56, 7605. doi: 10.1002/anie.201703012
43. [43]
  Wang, X.; Yakovliev, A.; Ohulchanskyy, T. Y.; Wu, L.; Zeng, S.; Han, X.; Qu, J.; Chen, G. Adv. Opt. Mater. 2018, 6, 1800690. doi: 10.1002/adom.201800690
44. [44]
  Wang, X.; Valiev, R. R.; Ohulchanskyy, T. Y.; Ågren, H.; Yang, C.; Chen, G. Chem. Soc. Rev. 2017, 46, 4150. doi: 10.1039/C7CS00053G
45. [45]
  Chen, G.; Damasco, J.; Qiu, H.; Shao, W.; Ohulchanskyy, T. Y.; Valiev, R. R.; Wu, X.; Han, G.; Wang, Y.; Yang, C.; Ågren, H.; Prasad, P. N. Nano Lett. 2015, 15, 7400. doi: 10.1021/acs.nanolett.5b02830
46. [46]
  Shao, W.; Chen, G.; Kuzmin, A.; Kutscher, H. L.; Pliss, A.; Ohulchanskyy, T. Y.; Prasad, P. N. J. Am. Chem. Soc. 2016, 138, 16192. doi: 10.1021/jacs.6b08973
47. [47]
  Liang, L.; Qin, X.; Zheng, K.; Liu, X. Acc. Chem. Res. 2018, 52, 228.
48. [48]
  Tu, L.; Liu, X.; Wu, F.; Zhang, H. Chem. Soc. Rev. 2015, 44, 1331. doi: 10.1039/C4CS00168K
49. [49]
  Haase, M.; Schäfer, H. Angew. Chem., Int. Ed. 2011, 50, 5808. doi: 10.1002/anie.201005159
50. [50]
  Liu, X.; Kong, X.; Zhang, Y.; Tu, L.; Wang, Y.; Zeng, Q.; Li, C.; Shi, Z.; Zhang, H. Chem. Commun. 2011, 47, 11957. doi: 10.1039/c1cc14774a
51. [51]
  Liang, L.; Xie, X.; Loong, D. T. B.; All, A. H.; Huang, L.; Liu, X. Chem.-Eur. J. 2016, 22, 10801. doi: 10.1002/chem.201602514
52. [52]
  Arboleda, C.; He, S.; Stubelius, A.; Johnson, N. J. J.; Almutairi, A. Chem. Mater. 2019, 31, 3103. doi: 10.1021/acs.chemmater.8b04057
53. [53]
  Chen, G.; Ohulchanskyy, T. Y.; Kumar, R.; Ågren, H.; Prasad, P. N. ACS Nano 2010, 4, 3163. doi: 10.1021/nn100457j
54. [54]
  Shen, B.; Cheng, S.; Gu, Y.; Ni, D.; Gao, Y.; Su, Q.; Feng, W.; Li, F. Nanoscale 2017, 9, 1964. doi: 10.1039/C6NR07687D
55. [55]
  Gargas, D. J.; Chan, E. M.; Ostrowski, A. D.; Aloni, S.; Altoe, M. V.; Barnard, E. S.; Sanii, B.; Urban, J. J.; Milliron, D. J.; Cohen, B. E.; Schuck, P. J. Nat. Nanotechnol. 2014, 9, 300. doi: 10.1038/nnano.2014.29
56. [56]
  Homann, C.; Krukewitt, L.; Frenzel, F.; Grauel, B.; Würth, C.; Resch-Genger, U.; Haase, M. Angew. Chem. Int. Ed. 2018, 57, 8765. doi: 10.1002/anie.201803083
57. [57]
  Tian, B.; Fernandez-Bravo, A.; Najafiaghdam, H.; Torquato, N. A.; Altoe, M. V. P.; Teitelboim, A.; Tajon, C. A.; Tian, Y.; Borys, N. J.; Barnard, E. S.; Anwar, M.; Chan, E. M.; Schuck, P. J.; Cohen, B. E. Nat. Commun. 2018, 9, 3082. doi: 10.1038/s41467-018-05577-8
58. [58]
  Johnson, N. J.; He, S.; Diao, S.; Chan, E. M.; Dai, H.; Almutairi, A. J. Am. Chem. Soc. 2017, 139, 3275. doi: 10.1021/jacs.7b00223
59. [59]
  Kuang, Y.; Xu, J.; Wang, C.; Li, T.; Gai, S.; He, F.; Yang, P.; Lin, J. Chem. Mater. 2019, 31, 7898. doi: 10.1021/acs.chemmater.9b01944
60. [60]
  Li, X.; Guo, Z.; Zhao, T.; Lu, Y.; Zhou, L.; Zhao, D.; Zhang, F. Angew. Chem. Int. Ed. 2016, 55, 2464. doi: 10.1002/anie.201510609
61. [61]
  Zhong, Y.; Ma, Z.; Zhu, S.; Yue, J.; Zhang, M.; Antaris, A. L.; Yuan, J.; Cui, R.; Wan, H.; Zhou, Y.; Wang, W.; Huang, N. F.; Luo, J.; Hu, Z.; Dai, H. Nat. Commun. 2017, 8, 737. doi: 10.1038/s41467-017-00917-6
62. [62]
  Chen, G.; Shen, J.; Ohulchanskyy, T. Y.; Patel, N. J.; Kutikov, A.; Li, Z.; Song, J.; Pandey, R. K.; Ågren, H.; Prasad, P. N.; Han, G. ACS Nano 2012, 6, 8280. doi: 10.1021/nn302972r
63. [63]
  Villa, I.; Vedda, A.; Cantarelli, I. X.; Pedroni, M.; Piccinelli, F.; Bettinelli, M.; Speghini, A.; Quintanilla, M.; Vetrone, F.; Rocha, U.; Jacinto, C.; Carrasco, E.; Rodríguez, F. S.; Juarranz, Á.; del Rosal, B.; Ortgies, D. H.; Gonzalez, P. H.; Solé, J. G.; García, D. J. Nano Research 2014, 8, 649.
64. [64]
  Diao, S.; Hong, G.; Antaris, A. L.; Blackburn, J. L.; Cheng, K.; Cheng, Z.; Dai, H. Nano Research 2015, 8, 3027. doi: 10.1007/s12274-015-0808-9
65. [65]
  Xie, X.; Li, Z.; Zhang, Y.; Guo, S.; Pendharkar, A. I.; Lu, M.; Huang, L.; Huang, W.; Han, G. Small 2017, 13, 1602843. doi: 10.1002/smll.201602843
66. [66]
  Liu, B.; Li, C.; Yang, P.; Hou, Z.; Lin, J. Adv. Mater. 2017, 29, 1605434. doi: 10.1002/adma.201605434
67. [67]
  Singh, S.; Smith, R. G.; Van Uitert, L. G. Phys. Rev. B 1974, 10, 2566. doi: 10.1103/PhysRevB.10.2566
68. [68]
  Wang, R.; Li, X.; Zhou, L.; Zhang, F. Angew. Chem. Int. Ed. 2014, 53, 12086. doi: 10.1002/anie.201407420
69. [69]
  Levy, E. S.; Tajon, C. A.; Bischof, T. S.; Iafrati, J.; Fernandez-Bravo, A.; Garfield, D. J.; Chamanzar, M.; Maharbiz, M. M.; Sohal, V. S.; Schuck, P. J.; Cohen, B. E.; Chan, E. M. ACS Nano 2016, 10, 8423. doi: 10.1021/acsnano.6b03288
70. [70]
  Zhang, H.; Fan, Y.; Pei, P.; Sun, C.; Lu, L.; Zhang, F. Angew. Chem. Int. Ed. 2019, 58, 10153. doi: 10.1002/anie.201903536
71. [71]
  Lu, Y.; Zhao, J.; Zhang, R.; Liu, Y.; Liu, D.; Goldys, E. M.; Yang, X.; Xi, P.; Sunna, A.; Lu, J.; Shi, Y.; Leif, R. C.; Huo, Y.; Shen, J.; Piper, J. A.; Robinson, J. P.; Jin, D. Nat. Photonics 2013, 8, 32.
72. [72]
  Fan, Y.; Wang, P.; Lu, Y.; Wang, R.; Zhou, L.; Zheng, X.; Li, X.; Piper, J. A.; Zhang, F. Nat. Nanotechnol. 2018, 13, 941. doi: 10.1038/s41565-018-0221-0
73. [73]
  Yao, C.; Wei, C.; Huang, Z.; Lu, Y.; El-Toni, A. M.; Ju, D.; Zhang, X.; Wang, W.; Zhang, F. ACS Appl. Mater. Interfaces 2016, 8, 6935. doi: 10.1021/acsami.6b01085
74. [74]
  Wilhelm, S.; Kaiser, M.; Wurth, C.; Heiland, J.; Carrillo-Carrion, C.; Muhr, V.; Wolfbeis, O. S.; Parak, W. J.; Resch-Genger, U.; Hirsch, T. Nanoscale 2015, 7, 1403. doi: 10.1039/C4NR05954A
75. [75]
  Muhr, V.; Wilhelm, S.; Hirsch, T.; Wolfbeis, O. S. Acc. Chem. Res. 2014, 47, 3481. doi: 10.1021/ar500253g
76. [76]
  Deng, Z.; Li, X.; Xue, Z.; Jiang, M.; Li, Y.; Zeng, S.; Liu, H. Nanoscale 2018, 10, 9393. doi: 10.1039/C8NR00305J
77. [77]
  Wang, P.; Fan, Y.; Lu, L.; Liu, L.; Fan, L.; Zhao, M.; Xie, Y.; Xu, C.; Zhang, F. Nat. Commun. 2018, 9, 2898. doi: 10.1038/s41467-018-05113-8
78. [78]
  Zhao, M.; Li, B.; Wang, P.; Lu, L.; Zhang, Z.; Liu, L.; Wang, S.; Li, D.; Wang, R.; Zhang, F. Adv. Mater. 2018, e1804982.
79. [79]
  Zhao, M.; Wang, R.; Li, B.; Fan, Y.; Wu, Y.; Zhu, X.; Zhang, F. Angew. Chem. Int. Ed. 2019, 58, 2050. doi: 10.1002/anie.201812878
80. [80]
  Wang, R.; Zhou, L.; Wang, W.; Li, X.; Zhang, F. Nat. Commun. 2017, 8, 14702. doi: 10.1038/ncomms14702
81. [81]
  Wang, S.; Liu, L.; Fan, Y.; El-Toni, A. M.; Alhoshan, M. S.; Li, D.; Zhang, F. Nano Lett. 2019, 19, 2418. doi: 10.1021/acs.nanolett.8b05148
82. [82]
  Peng, J.; Samanta, A.; Zeng, X.; Han, S.; Wang, L.; Su, D.; Loong, D. T. B.; Kang, N.-Y.; Park, S.-J.; All, A. H.; Jiang, W.; Yuan, L.; Liu, X.; Chang, Y.-T. Angew. Chem. Int. Ed. 2017, 56, 4165. doi: 10.1002/anie.201612020
83. [83]
  Yang, D.; Ma, P. A.; Hou, Z.; Cheng, Z.; Li, C.; Lin, J. Chem. Soc. Rev. 2015, 44, 1416. doi: 10.1039/C4CS00155A
84. [84]
  Hou, Z.; Zhang, Y.; Deng, K.; Chen, Y.; Li, X.; Deng, X.; Cheng, Z.; Lian, H.; Li, C.; Lin, J. ACS Nano 2015, 9, 2584. doi: 10.1021/nn506107c
85. [85]
  Oliveira, H.; Bednarkiewicz, A.; Falk, A.; Frohlich, E.; Lisjak, D.; Prina-Mello, A.; Resch, S.; Schimpel, C.; Vrcek, I. V.; Wysokinska, E.; Gorris, H. H. Adv. Healthc. Mater. 2019, 8, e1801233.
86. [86]
  Gnach, A.; Lipinski, T.; Bednarkiewicz, A.; Rybka, J.; Capobianco, J. A. Chem. Soc. Rev. 2015, 44, 1561. doi: 10.1039/C4CS00177J
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13. [13]
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16. [16]
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19. [19]
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20. [20]
  . . Chinese Journal of Inorganic Chemistry, 2024, 40(12): 0-0.

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沈阳化工大学材料科学与工程学院沈阳 110142