Citation: Chi Jingyuan, Li Jing, Ren Shaokang, Su Shao, Wang Lianhui. Construction and Application of DNA-two-dimensional Layered Nanomaterials Sensing Platform[J]. Acta Chimica Sinica, ;2019, 77(12): 1230-1238. doi: 10.6023/A19070262 shu

Construction and Application of DNA-two-dimensional Layered Nanomaterials Sensing Platform

Key Laboratory for Organic Electronics and Information Displays(KLOEID) & Jiangsu Key Laboratory for Biosensors, School of Materials Science and Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210023, China

Corresponding author: Wang Lianhui, iamlhwang@njupt.edu.cn
Received Date: 12 July 2019
Available Online: 18 December 2019
Fund Project: Project supported by the National Key Research and Development Program of China (No. 2017YFA0205302), the National Natural Science Foundation of China (Nos. 61671250, 21475064) and the Jiangsu College Students' innovation and entrepreneurship training program (No. SZD2018013)the National Natural Science Foundation of China 61671250the National Key Research and Development Program of China 2017YFA0205302the Jiangsu College Students' innovation and entrepreneurship training program SZD2018013the National Natural Science Foundation of China 21475064

Figures(7)

Combining the specific recognition ability of DNA molecules with the superior physical and chemical properties of two-dimensional (2D) layered materials, a DNA-2D layered nanomaterial sensing platform was constructed. More and more researchers are devoted to develop this sensing platform, which has become one of the important research directions in the field of chemical/biological sensors. In view of the rapid development of the 2D layered materials, this paper firstly introduces the construction principle of the DNA-2D layered material sensing platform. Then we mainly review the application of the sensing platform in the analysis of chemical and biological molecules, including metal ions, mycotoxins, ATP, amino acid, antibiotics, nucleic acids, proteins and cancer cells. Finally, the future of this sensing platform is prospected.
- two-dimensional layered nanomaterial,
- DNA,
- sensing platform,
- analysis
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沈阳化工大学材料科学与工程学院沈阳 110142