Citation: Jin Xin, Wang XiaoYing. Progress in Analysis and Detection of Salivary Tumor Biomarkers Associated with Oral Cancer[J]. Acta Chimica Sinica, ;2019, 77(4): 340-350. doi: 10.6023/A18100414 shu

Progress in Analysis and Detection of Salivary Tumor Biomarkers Associated with Oral Cancer

Jin Xin ,
Wang XiaoYing ^,

Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China

Corresponding author: Wang XiaoYing, wxy@seu.edu.cn
Received Date: 7 October 2018
Available Online: 3 April 2018
Fund Project: the National Natural Science Foundation of China 81600179Project supported by the National Natural Science Foundation of China (Nos. 81600179, 81302472) and "Blue Project" funded by universities in Jiangsuthe National Natural Science Foundation of China 81302472

Figures(9)

Oral cancer is head and neck cancer, and cancer tissue is located in the oral cavity. The non-invasive early diagnosis is an effective method to reduce the death of the disease. The oral cancer-related substances are first released into the saliva, which is convenient, safe and non-invasive, and is the first choice for screening and early diagnosis of oral cancer. In this paper, the specific types and the commonly used detection methods of the salivary tumor biomarkers at home and abroad were summarized and compared. Specifically, the latest application of new electrochemical biosensor in the detection of the salivary tumor biomarkers associated with oral cancer was mainly described. Futhermore, the summary of its future directions and the potential applications was proposed, which provided reference for the further research and application of the salivary tumor biomarkers in oral cancer.
- oral cancer,
- saliva,
- tumor biomarker,
- detection technology,
- electrochemical biosensor
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沈阳化工大学材料科学与工程学院沈阳 110142