Citation: Zhao Keli, Hao Ying, Zhu Mo, Cheng Guosheng. A Review: Biodegradation Strategy of Graphene-Based Materials[J]. Acta Chimica Sinica, ;2018, 76(3): 168-176. doi: 10.6023/A17110499 shu

A Review: Biodegradation Strategy of Graphene-Based Materials

Zhao Keli ^a,b ,
Hao Ying ^a ,
Zhu Mo ^a,c ,
Cheng Guosheng ^a,b,,

a.
CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Jiangsu 215123
b.
University of Chinese Academy of Sciences, Beijing 100049
c.
University of Shanghai, Shanghai 200444

Corresponding author: Cheng Guosheng, gscheng2006@sinano.ac.cn
Received Date: 22 November 2017
Available Online: 7 March 2018
Fund Project: the National Key Basic Research Program of China 2014CB965003the National Key Basic Research Program of China 973 ProgramProject supported by the National Key Basic Research Program of China (973 Program, No. 2014CB965003)

Figures(6)

Since its discovery in 2004, the new frontier materials graphene and its derivatives have attracted a great deal of attention on the fields of new batteries, sensors, new energy and biomedicine, due to their unique electrical, optical and mechanical properties. Specifically, it has been developed rapidly in the biomedical field. The good biocompatibility has endowed graphene and its derivatives great prospects for their biological applications. In order to realize the in vivo application of graphene materials and improve the safety of the environment and life system, it is crucial to consider and study on the biodegradation behaviors of graphene. The research on biodegradation of graphene currently mainly focuses on the enzymatic degradation. The degradation behaviors can be tuned by the modification via a series of methods, such as heterogeneous atom doping and surface functionalization, etc. The progress of biodegradation of graphene and their derivatives, especially the enzymatic degradation and their biomedical applications is discussed. The important basis and guidance to further promote the in vivo study of graphene materials will be provided.
- graphene,
- biocompatibility,
- enzymatic degradation,
- surface modification
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沈阳化工大学材料科学与工程学院沈阳 110142