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Citation: DUAN Zhengchao, WANG Lianzhi, QU Taoli, ZUO Xiaoyu, HU Xiangping, ZHENG Zhuo. Enantioselective Synthesis of Chiral 2-Phenylpropanol via Rh-catalyzed Asymmetric Hydrogenation of 2-Phenylprop-2-en-1-ol[J]. Chinese Journal of Applied Chemistry, ;2014, 31(11): 1356-1358. doi: 10.3724/SP.J.1095.2014.40054 shu

Enantioselective Synthesis of Chiral 2-Phenylpropanol via Rh-catalyzed Asymmetric Hydrogenation of 2-Phenylprop-2-en-1-ol

1.
a School of Chemical and Environmental Engineering, Hubei University for Nationalities, Enshi 445000, China;
2.
b Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China

Corresponding author: DUAN Zhengchao, HU Xiangping,
Received Date: 25 February 2014
Available Online: 7 May 2014
Fund Project: 国家自然科学基金资助项目(21262011) (21262011)

Rhodium-catalyzed asymmetric hydrogenation of 2-phenylprop-2-en-1-ol was investigated for the first time.Enantioselective synthesis of chiral 2-phenylpropanol with up to 70% ee was achieved through screen on a series of monodentate ligands and bidentate ligands.
- chiral phenylpropanol,
- Rh(Ⅰ) complex,
- asymmetric catalytic hydrogenation,
- phenylprop-en-ol,
- chiral phosphorus ligand
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