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Citation: ZHAO Zhouxing. One-pot Synthesis of Aroyl Cyanides Under Solvent-free and Catalyst-free Conditions[J]. Chinese Journal of Applied Chemistry, ;2014, 31(8): 943-946. doi: 10.3724/SP.J.1095.2014.30524 shu

One-pot Synthesis of Aroyl Cyanides Under Solvent-free and Catalyst-free Conditions

ZHAO Zhouxing ^,

1.
College of Chemical Engineering, Qinghai University, Xining 810016, China

Corresponding author: ZHAO Zhouxing,
Received Date: 24 October 2013
Available Online: 24 February 2014
Fund Project:

A series of aroyl cyanides was synthesized by nucleophilic substitution reactions of aromatic acids with thionyl chloride and potassium ferricyanide in one-pot under solvent-free and catalyst-free conditions. The effects of the reaction temperature and time on the yield of the products were investigated. The yields of aroyl cyanides were up to 71%~92% when the reactions were performed at 180℃ for 2 h. The structures of the products were confirmed by IR,¹H NMR and ¹³C NMR spectroscopy. This method has advantages of simple work-up procedure,high yield,and eco-friendly solvent-free and catalyst-free conditions.
- one-pot,
- solvent-free,
- aromatic acyl chloride,
- aroyl cyanides,
- synthesis
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