Citation: Li-Lei REN, Li-Wei XIAO, Guang-Xian LIU, Ming-Ming XU. Synthesis of Cyclopenta[d]pyrimidinones and Hexahydroquinazolinones Catalyzed by Activated Carbon Supported Sulfuric Acid[J]. Chinese Journal of Applied Chemistry, ;2021, 38(1): 44-50. doi: 10.19894/j.issn.1000-0518.190334 shu

Synthesis of Cyclopenta[d]pyrimidinones and Hexahydroquinazolinones Catalyzed by Activated Carbon Supported Sulfuric Acid

Faculty of Chemistry and Material Science, Langfang Normal University, Langfang 065000, China

Corresponding author: Li-Lei REN, renll1409@163.com Li-Wei XIAO, xiaoliwei2000@sina.com
Received Date: 13 December 2019
Accepted Date: 30 September 2020

Fund Project: the Educational Commission of Hebei Province ZD2020153the Science and Technology of Langfang 2019011018

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An activated carbon supported sulfuric acid catalyst (H₂SO₄/AC) was prepared and characterized by Fourier transform infrared (FT-IR) spectrometry and X-ray diffraction (XRD). Various cyclopenta[d]pyrimidinones and hexahydroquinazolinones were synthesized by the reaction of aromatic aldehyde with urea and cyclopentone(cyclohexanone) catalyzed by H₂SO₄/AC in the absence of solvent. This method is simple and environmentally benign. The catalyst can be easily recovered and its activity maintains after being reused for 3 times.
- Activated carbon supported sulfuric acid,
- Cyclopenta[d]pyrimidinones,
- Hexahydroquinazolinones,
- Multicomponent reactions
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