Citation: JIN Yuting, ZHI Defu, GUO Yongtai, SUI Yue, SUN Lei, ZWANG Qian, HAO Longxuan, ZHAO Chunhui. Whitening and Antioxidant Activities of Phenolic Derivatives[J]. Chinese Journal of Applied Chemistry, ;2019, 36(11): 1257-1265. doi: 10.11944/j.issn.1000-0518.2019.11.190139 shu

Whitening and Antioxidant Activities of Phenolic Derivatives

JIN Yuting ^a ,
ZHI Defu ^c ,
GUO Yongtai ^a ,
SUI Yue ^a ,
SUN Lei ^a ,
ZWANG Qian ^a ,
HAO Longxuan ^a,b,, ,
ZHAO Chunhui ^b,,

a.
Liaoning Normal University, School of Chemistry and Chemical Engineering, Dalian, Liaoning 116029, China
b.
Liaoning Normal University Liaoning Provincial Key Laboratory of Biotechnology and Drug Discovery, Dalian, Liaoning 116029, China
c.
Dalian Nationalities University College of Life Science, Dalian, Liaoning 116600, China

Corresponding author: HAO Longxuan, lxzhao@lnnu.edu.cn ZHAO Chunhui, zch@lnnu.edu.cn
Received Date: 14 May 2019
Revised Date: 23 July 2019
Accepted Date: 19 August 2019

Fund Project: Supported by the National Natural Science Foundation of China(No.21101067)the National Natural Science Foundation of China 21101067

Figures(1)

A series of phenolic derivatives was synthesized and characterized by Fourier transform infrared spectrometer(FTIR), nuclear magnetic resonance spectroscopy(NMR) and electrospray ionisation mass spectrometry(ESI-MS). Their whitening activity was also tested. The results showed that the tyrosinase inhibitory activities HB-1(0.229±0.026), HB-3a(0.829±0.135), HB-3b(0.446±0.047), HMB-3a(1.747±0.215), HMB-3b(1.307±0.058) and HPE-4b(2.501±0.261) were significantly better than those of the positive control, α-arbutin (3.60±0.029). The antioxidant activities of these compounds were tested to whitening potentials. The results showed that the antioxidant activities of HB-3b and HMB-3a were comparable to the positive control substance quercetin and lycopene. Therefore, such compounds can be developed and utilized as whitening agents and antioxidants.>
- penolic compounds,
- tyrosinase inhibitor,
- anti-oxidant
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