Citation: TANG Yucai, WANG Ping, RAN Shutong, CHEN Piao. Synthesis of (E)-β-Vinyl Sulfones by Metal-Free Tetrabutylammonium Iodide/Potassium Persulfate Mediated Radical Denitrative Sulfonylation of β-Nitrostyrenes with Sulfonylhydrazides[J]. Chinese Journal of Applied Chemistry, ;2019, 36(6): 664-670. doi: 10.11944/j.issn.1000-0518.2019.06.180338 shu

Synthesis of (E)-β-Vinyl Sulfones by Metal-Free Tetrabutylammonium Iodide/Potassium Persulfate Mediated Radical Denitrative Sulfonylation of β-Nitrostyrenes with Sulfonylhydrazides

TANG Yucai ^a,b,, ,
WANG Ping ^a ,
RAN Shutong ^a ,
CHEN Piao ^a

a.
College of Chemistry and Materials Engineering
b.
College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde, Hunan 415000, China

Corresponding author: TANG Yucai, yctang1009@163.com
Received Date: 26 October 2018
Revised Date: 21 December 2018
Accepted Date: 14 January 2019

Fund Project: the Start-up Foundation for Doctors of Hunan University of Arts and Science 17BSQD32Supported by the Start-up Foundation for Doctors of Hunan University of Arts and Science(No.17BSQD32), the Construct Program of the Key Discipline in Hunan Province(Applied Chemistry)

Figures(3)

A novel and efficient protocol towards (E)-β-vinyl sulfone derivatives by tetrabutylammonium Iodide(TBAI)/K₂S₂O₈ mediated denitrative sulfonylation of readily prepared β-nitrostyrenes and economical sulfonylhydrazides was described. The corresponding (E)-β-vinyl sulfone compounds were obtained in moderate to good yields. Compared with reported methods, the present strategy features metal-free, acid and base-free.
- (E)-β-vinyl sulfone,
- β-nitrostyrenes,
- sulfonylhydrazides,
- denitrative sulfonylation,
- radical reaction
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