Citation: WANG Hongyan, WEI Xuning. Preparation of 3-Arylthio-4-hydroxycoumarin and Its Analogs[J]. Chinese Journal of Applied Chemistry, ;2018, 35(10): 1184-1189. doi: 10.11944/j.issn.1000-0518.2018.10.170406 shu

Preparation of 3-Arylthio-4-hydroxycoumarin and Its Analogs

WANG Hongyan ^, ,
WEI Xuning

School of Chemical Engineering and Environment, He'nan University of Technology, Zhengzhou 450001, China

Corresponding author: WANG Hongyan, 18623717897@163.com
Received Date: 14 November 2017
Revised Date: 5 February 2018
Accepted Date: 6 March 2018

Fund Project: the Transformation and Utilization of Grain Resources in Henan Province Key Laboratory Open Project 24400037Support by the Transformation and Utilization of Grain Resources in Henan Province Key Laboratory Open Project(No.24400037)

Figures(3)

4-Hydroxylcoumarin and its analogs are one of the most active classes of heterocyclic compounds. Many of these compounds have been proved to have a wide range of biological and pharmacological activities, such as antibacterial, anti-tumor, anti-HIV. Herein, 3-arylthio-4-hydroxycoumarin and its analogs were synthesized from stable non-toxic 4-hydroxycoumarins, iodobenzenes and sulfur in a cheap and environmentally friendly fashion.
- arylthio-hydroxycoumarin,
- arylthio-hydroxyquinolinone,
- aryl-thiolation
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