Citation: LI Zhuheng, LIU Xia, LIU Dianjun, WANG Zhenxin. Application of Protein Microarray in Clinical Analsis[J]. Chinese Journal of Applied Chemistry, ;2016, 33(11): 1253-1264. doi: 10.11944/j.issn.1000-0518.2016.11.160315 shu

Application of Protein Microarray in Clinical Analsis

LI Zhuheng ^a,b ,
LIU Xia ^b ,
LIU Dianjun ^b ,
WANG Zhenxin ^b,,

1.
a Jilin Provincial Institute of Education, Changchun 130024, China;
2.
b State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

Corresponding author: WANG Zhenxin,
Received Date: 10 August 2016
Available Online: 20 September 2016
Fund Project:

Protein microarray is capable of high-throughput monitoring biological toxins, analyzing the host-microbe interactions and the antigen-antibody interaction, and screening biomarkers of diseases. Therefore, protein microarray is expected to become one of the main technology of in vitro diagnostic and plays an important role in precision medicine of many diseases, such as pathogen infection, autoimmune diseases, neurodegenerative diseases, cancer and so on. Through analyzing the recently published research results, this review summarizes recent progress of protein microarray in the clinical analysis, analyzes the technical challenges in practical application, and discusses corresponding solutions.
- protein microarray,
- clinical detection,
- high-throughput analysis,
- biological molecular interaction
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沈阳化工大学材料科学与工程学院沈阳 110142