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Citation: Chengyan XU, Jiangnan YU, Yu LI, Xizhen PAN, Yinlin HOU, Wenmin WANG. Synthesis, structure, and bioactivity of a Ho4 complex bridged by azide group[J]. Chinese Journal of Inorganic Chemistry, ;2026, 42(7): 1453-1462. doi: 10.11862/CJIC.20260033 shu

Synthesis, structure, and bioactivity of a Ho4 complex bridged by azide group

  • School of Scince, Kaili University, Kaili, Guizhou 556011, China

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  • A new azide bridged tetranuclear Ho(Ⅲ)-based complex with the formula[Ho4(L)4(NO3)2(N3)2(μ2-N3)4]·CH3OH (1) has been constructed via the solvothermal method by using Schiff base ligands (HL=N′-[(6-methoxypyridin-2-yl)methylidene]pyridine-2-carbohydrazide), Ho(NO3)3·6H2O, and NaN3. Single-crystal X-ray diffraction reveals that the structure of complex 1 is mainly composed of four Ho(Ⅲ) ions, four L- ions, two NO3- ions, two N3- ions and four μ2-N3- ions. The four central Ho(Ⅲ) ions are connected by four μ2-O atoms and four μ3-N3- atoms forming a parallelogram Ho4 core. The interaction between complex 1 and calf thymus DNA was studied by cyclic voltammetry, gel electrophoresis, ultraviolet spectroscopy, and fluorescence spectroscopy. The results revealed that complex 1 could bind to calf thymus DNA mainly by intercalation.
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