Citation: Lifang HE, Yaoze LUO, Qiying SHI, Jianxin TANG, Fuxing ZHANG, Xiaoming ZHU. Synthesis, structure, and properties of hydrated tricyclohexyltin theophylline-7-acetic acid complex[J]. Chinese Journal of Inorganic Chemistry, ;2026, 42(3): 632-640. doi: 10.11862/CJIC.20250244 shu

Synthesis, structure, and properties of hydrated tricyclohexyltin theophylline-7-acetic acid complex

Lifang HE ^{1, 2} ,
Yaoze LUO ³ ,
Qiying SHI ³ ,
Jianxin TANG ³ ,
Fuxing ZHANG ^{2, 3, 4,,} ,
Xiaoming ZHU ^{2, 3, 4}

1.
Department of Life Sciences, Hengyang Normal University, Hengyang, Hunan 421008, China
2.
Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Hengyang Normal University, Hengyang, Hunan 421008, China
3.
Department of Chemistry and Material Science, Hengyang Normal University, Hengyang, Hunan 421008, China
4.
Key Laboratory of Organometallic New Materials of University of Hunan Province, Hengyang Normal University, Hengyang, Hunan 421008, China

Corresponding author: Fuxing ZHANG, zfx8056@163.com
Received Date: 29 July 2025
Revised Date: 14 December 2025

Figures(6)

The hydrated tricyclohexyltin theophylline-7-acetic acid (tpH) complex [Sn(C₆H₁₁)₃(tp)(H₂O)] was synthesized via an ethanol solvothermal method using tricyclohexyltin hydroxide and tpH in a 1∶1 molar ratio. The complex was characterized by IR, ¹H (¹³C) NMR, elemental analysis, and powder X-ray diffraction, and the crystal structure was determined by single-crystal X-ray diffraction. The crystal belongs to the orthorhombic system with space group Iba2, and the central tin atom is in a five-coordinated trigonal bipyramidal configuration. Quantum chemistry ab initio calculations were performed to investigate the stability, molecular orbital energy, and frontier molecular orbital characteristics of the complex. Additionally, its thermal stability, electrochemical properties, and in vitro anticancer activity were evaluated.
- hydrated tricyclohexyltin theophylline-7-acetic acid complex,
- synthesis,
- crystal structure,
- in vitro antitumor activity
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