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Citation: Hao BAI, Weizhi JI, Jinyan CHEN, Hongji LI, Mingji LI. Preparation of Cu2O/Cu-vertical graphene microelectrode and detection of uric acid/electroencephalogram[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(7): 1309-1319. doi: 10.11862/CJIC.20240001 shu

Preparation of Cu2O/Cu-vertical graphene microelectrode and detection of uric acid/electroencephalogram

  • 1.

    School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384, China

  • 2.

    School of Integrated Circuit Science and Engineering, Tianjin University of Technology, Tianjin 300384, China

Figures(10)

  • A Cu2O/Cu-vertical graphene microelectrode was prepared by combining Cu(Ⅱ) ion impregnation adsorption and direct current (DC) arc plasma jet chemical vapor deposition methods for dual functions including electro-chemical detection of uric acid and recording electroencephalogram (EEG) signals. The morphology, microstructure, and crystal composition of the microelectrode were characterized using scanning electron microscopy, transmission electron microscopy, and X-ray diffraction, and the electrochemical and EEG recording capabilities were evaluated. The microelectrode was composed of vertically grown graphene nanosheets embedded with Cu2O/Cu nanoparticles, with a diameter of approximately 200 μm. Because these nanosheets are arranged into a three-dimensional porous structure, the microelectrode has a short ion diffusion path and a long conductive network, which promotes high elec-trocatalytic activity and electrical performance. The scalp-contact resistance of the microelectrode with physiological saline was as low as 7.05 kΩ. The signal-to-noise ratios of electromyography (EMG), electrooculogram (EOG), and EEG of the microelectrode were close to or exceeded those of a commercial wet electrode coated with conductive gel. In addition, the microelectrode also electrochemically responded to uric acid, with a wide concentration range of 0.5-500 μmol·L-1 and a low detection limit of 0.024 μmol·L-1, as well as excellent anti-interference and long-term stability.
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