Citation: Yun-Ze XU, Jin-Bei SHEN, Guo-Liang ZHAO, Wei-Ji HU. Syntheses, Crystal Structures and DNA-Binding of Two Manganese Complexes[J]. Chinese Journal of Inorganic Chemistry, ;2022, 38(2): 285-294. doi: 10.11862/CJIC.2022.038 shu

Syntheses, Crystal Structures and DNA-Binding of Two Manganese Complexes

Yun-Ze XU ¹ ,
Jin-Bei SHEN ¹ ,
Guo-Liang ZHAO ^{1, 2,,} ,
Wei-Ji HU ³

1.
College of Chemistry and Life Science, Zhejiang Normal University, Jinhua, Zhejiang 321004, China
2.
Xingzhi College, Zhejiang Normal University, Jinhua, Zhejiang 321004, China
3.
Ningbo University of Technology, Ningbo, Zhejiang 315211, China

Corresponding author: Guo-Liang ZHAO, sky53@zjnu.cn
Received Date: 2 August 2021
Revised Date: 18 December 2021

Figures(9)

Coordination polymer[Mn₃(L)₆(H₂O)₄]_n (1) was prepared by the reaction of manganese chloride (MnCl₂·4H₂O) and 4-methyl-1, 2, 3-thiadiazole-5-carboxylic acid (HL) by conventional solution method, and complex[Mn₂(phen)₄(H₂O)₂Cl₂](L)₂·3H₂O (2) was synthesized after adding the ligand 1, 10-phenanthroline (phen). The complexes were characterized by elemental analysis, infrared spectroscopy, thermogravimetric analysis, and singlecrystal X-ray diffraction. The single-crystal structure analysis shows that complex 1 belongs to the monoclinic system, P2₁/c space group. The three manganese ions are bridged in bidentate fashion by the oxygen atoms in the six thiadiazole formate groups to form a linear trinuclear molecule cluster compound. The cluster unit is connected by the coordination of nitrogen atom from one of the thiadiazole rings and the manganese atom of the other cluster unit to form a layered structure. Complex 2 belongs to the triclinic crystal system, P1 space group. The central metal manganese ion coordinated with four nitrogen atoms from two phen molecules, one chloride anion, and one oxygen atom of coordination water molecule respectively, forming a six-coordinated twisted octahedral structure cation. The thiadiazole formate anion plays the role of charge balance. Ethidium bromide fluorescence spectrometry was used to determine the interaction between HL and complexes with DNA, respectively. The results showed that the interaction between the complexes and DNA was stronger than that of HL, and complex 2 with a planar ligand had a stronger effect than that of complex 1.
- 4-methyl-1, 2, 3-thiadiazol-5-carboxylic acid,
- manganese,
- complex,
- crystal structure,
- DNA-binding
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