Citation: Yan-Ling LIU. Synthesis and Performance of a Rapid Turn-On Fluorescent Probe for ClO^-[J]. Chinese Journal of Inorganic Chemistry, ;2021, 37(12): 2244-2248. doi: 10.11862/CJIC.2021.259 shu

Synthesis and Performance of a Rapid Turn-On Fluorescent Probe for ClO^-

Yan-Ling LIU ^,

Department of Chemistry and Chemical Engineering, Lüliang University, Lüliang, Shanxi 033001, China

Corresponding author: Yan-Ling LIU, 20001015@llu.edu.cn
Received Date: 30 September 2021
Revised Date: 14 November 2021

Figures(8)

We synthesized a new type of ClO^- fluorescence probe using 2, 7-dibromo-9-fluorenone as raw material by two-step conventional reaction. In phosphate buffered saline (PBS), with the increase of ClO^-, the emission of the probe at 511 nm gradually enhanced, presenting green fluorescence emission. The probe reacted with ClO^- quickly and the reaction was completed within 10 s. In addition, the present method exhibited high sensitivity to ClO^- with a limit of detection of 0.74 μmol·L^-1. Cell image experiments showed that the probe could detect endogenous and exogenous ClO^- at the cellular level.
- turn-on type,
- hypochlorite,
- fluorescent probe,
- cell imaging
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沈阳化工大学材料科学与工程学院沈阳 110142

Synthesis and Performance of a Rapid Turn-On Fluorescent Probe for ClO-

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通讯作者: 陈斌, bchen63@163.com

Synthesis and Performance of a Rapid Turn-On Fluorescent Probe for ClO^-