Citation: YANG Zheng, XIE An-Jian, SHEN Yu-Hua. pH-Controlled Drug Release of Nitrogen Doped Carbon Dots Delivering Doxorubicine for Synergetic Photo-Thermal Therapy and Chemotherapy[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(10): 1775-1782. doi: 10.11862/CJIC.2018.236 shu

pH-Controlled Drug Release of Nitrogen Doped Carbon Dots Delivering Doxorubicine for Synergetic Photo-Thermal Therapy and Chemotherapy

School of Chemistry and Chemical Engineering, Collaborative Innovation Center of Modern Bio-Manufacture, Anhui University, Hefei 230601, China

Corresponding author: SHEN Yu-Hua, s_yuhua@163.com
Received Date: 21 June 2018
Revised Date: 22 August 2018

Figures(5)

A brand new treatment was reported to cure the cancer triumphantly using the combination of photo-thermal therapy inducing by nitrogen doped carbon dots (N-CDs) and chemotherapy of the doxorubicin (Dox). The experiment results demonstrated that the as-synthesized N-CDs had excellent photo-thermal effect inducing the temperature enhancement as high as about 10℃. Furthermore, the as-prepared N-CDs could load Dox availably and achieve a pH-controlled drug release. Thus, the multifunctional N-CDs-Dox nanocomposites could perform the synergetic effect of photo-thermal therapy and chemotherapy to tumor cells.
- pH-controlled drug release,
- antitumor agents,
- nitrogen doped carbon dots,
- drug deliver,
- hydrothermal synthesis,
- photo-thermal therapy,
- chemotherapy,
- synergistic effect
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