Citation: HUANG Qiu-Ying, HAN Yin-Feng, ZHENG Ze-Bao. Synthesis and Properties of a Calix[4]arene-Based Ruthenium(Ⅱ) Complex[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(2): 217-229. doi: 10.11862/CJIC.2018.021 shu

Synthesis and Properties of a Calix[4]arene-Based Ruthenium(Ⅱ) Complex

1.
Department of Chemical Engineering, Henan Polytechnic Institute, Nanyang, Henan 473009, China
2.
College of Chemistry and Chemical Engineering, Taishan University, Tai'an, Shandong 271021, China

Corresponding author: HUANG Qiu-Ying, huangqy72@163.com ZHENG Ze-Bao, zhengzebao@163.com
Received Date: 19 July 2017
Revised Date: 22 October 2017

Figures(10)

A new calix[4]arene-based ruthenium(Ⅱ) complex of[Ru₂(bpy)₄(H₂L)](ClO₄)₄ (1) (bpy=2, 2'-bipyridine and H₂L=11, 23-bis(2-imidazo[4, 5-f]-1, 10-phenanthroline)-25, 27-dihydroxy-26, 28-diethoxycarbonylpropyl-5, 17-di-p-t-butyl-calix[4]arene) was synthesized and characterized using an assortment of spectroscopic techniques such as IR, ¹H NMR, ¹³C NMR, ESI-MS, and elementary analysis. The pH luminescence switching property of 1 was studied by means of spectrofluorimetric titrations in CH₃CN/Britton-Robinson buffer solution (1: 100, V/V). The complex exhibited two-step separate protonation/deprotonation processes, and acting as a pH-induced "off-on-off" luminescence switch (I_on/I_off=1.42 and 96.0). The anion sensing properties of complex 1 were thoroughly investigated in solution using absorption, emission, and ¹H NMR spectral studies, which revealed that 1 acted as an efficient "turn off" emission sensor for F^- and OAc^-. Importantly, cellular imaging and cytotoxicity experiments demonstrated that 1 rapidly penetrate through the HeLa cells membrane, and showed low cytotoxicity at the imaging concentration.
- ruthenium(Ⅱ) complex,
- calix[4]arene,
- pH switch,
- anion sensing,
- cell imaging
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沈阳化工大学材料科学与工程学院沈阳 110142