“General Chemistry”是面向中外合作办学工科专业学生开设的一门学科基础课。为了提升教学质量，课程引入国外经典教材，在教学过程中面临外来文化的冲击和文化自信缺失的风险。因此，必须通过“General Chemistry”课程思政教学提升学生对自身文化的深度认同。本文中，“General Chemistry”课程思政建设坚持文化自信理念，积极挖掘中国思政元素，将中外思政元素合理融入到教学的每一个环节，不断助推课程思政教学内涵式发展，打造课程思政高效课堂，取得了较好的育人成效。

Two complexes [Cd(L)(CH₃O)(CH₃COO)]·CH₃OH·(CH₃)₂NH (C1) and [Mn(L)Cl₂(CH₃OH)] (C2) were synthesized by reacting a new imidazole-bearing ligand 4-(1H-imidazol-1-yl)-N′-(pyridin-2-ylmethylene)benzohydrazide (L) with cadmium and manganese salts, respectively. The ligand was characterized by ¹H NMR and ¹³C NMR spectroscopy, while the complexes were analyzed by single-crystal X-ray diffraction, powder X-ray diffraction, thermogravimetric analyses, and UV-Vis spectroscopy. Complex C1 features a 1D zigzag chain structure formed by alternating connections of one ligand and one metal ion. In contrast, complex C2 exhibits a mononuclear molecular structure, where each unit consists of one ligand connected to one manganese ion. Both complexes further form a 3D structure through π-π interactions and intermolecular hydrogen bonds. Cell proliferation assays conducted on four tumor cell lines and one normal cell line revealed that both C1 and C2 exhibited significantly stronger inhibition of tumor cell growth compared to the ligand L. Notably, C1 demonstrated superior anti-proliferative activity against A549 and A2780 cells relative to cisplatin, while showing comparable cytotoxicity toward SMMC-7721 cells. Further mechanistic studies indicated that C1 induces apoptosis in both SMMC-7721 and A549 tumor cells, suppresses the invasion and migration of SMMC-7721 cells, and arrests the cell cycle at the G0/G1 phase.