Under ultra-high vacuum, surface synthesis of 2D conjugated metal-organic frameworks (MOFs) was carried out through molecular beam epitaxy (MBE) growth to address the challenge of traditional solvothermal methods in achieving large-scale, defect-free single-crystal synthesis. Here, we chose an iconic 2D conjugated MOF, Cu₃(HOTP)₂ (HOTP represents the deprotonated derivative of 2,3,6,7,10,11-hexahydroxytriphenylene), as a case study to investigate the diversified self-assembly of Cu atoms and HHTP ligands, as well as the synthesis mechanism of the MOF fragment on the surface with and without O₂ annealing conditions by scanning tunneling microscopy. The results show that dumbbell-shaped [Cu(HOTP)₂] complexes, the target fragment of MOFs, can be successfully generated in an O₂ atmosphere, yet large-area extended MOFs remain elusive, highlighting oxidation and ligand deprotonation as two key factors that hinder the on-surface synthesis of Cu₃(HOTP)₂.

关注牛奶安全这一国计民生问题，将分子印迹前沿技术引入本科实验课堂，设计了一个综合实验。融合分子印迹、蛋白质排阻、磁性分离等技术制备得到磁性分子印迹聚合物，考察其性能，并以其作为固相萃取吸附剂，结合高效液相色谱，建立直接选择性检测牛奶样品中痕量四环素的新方法。本实验涉及材料化学、分析化学、仪器分析、食品化学等多学科知识，培养学生的科学素养、综合解决复杂问题的能力和创新性思维。印迹材料的设计和磁性分离过程富有创新性和趣味性，整个实验过程成本低廉、易操作、安全性高。通过本实验，学生能够了解分子印迹前沿技术，学习新检测方法的建立，巩固实验基础操作，提高数据采集和分析能力，加深对组分-性能-应用关系的理解。

高分子化学实验不仅是提升学生实验技能与实践能力的关键途径，更是培育学生创新思维及科研素养的重要环节。为切实提高实验教学效果和质量，充分激发学生主动学习的内驱力，全面培养探索精神、创新能力和思辨思维，我校高分子化学及实验教学组积极开展教学改革探索和实践,首先，精心设计教学内容,确保知识的关联性和实用性；其次，革新实验教学方法，增强实验教学的互动性和创新性；再次，完善教学评价机制，强化过程考核；最后，全面融入课程思政，实现知识传授与价值引领的有机统一。