Citation: Jia Xi XU, Sheng JIN, Meng Shen CAI. DESIGN,SYNTHESIS AND ACTIVITIES OF ANALOGS AND SEGMENTS OF THE PAPAVER SOMNIFERUM POLLEN PEPTIDE PSPP2[J]. Chinese Chemical Letters, ;1995, 6(11): 941-942. shu

DESIGN,SYNTHESIS AND ACTIVITIES OF ANALOGS AND SEGMENTS OF THE PAPAVER SOMNIFERUM POLLEN PEPTIDE PSPP2

a School of Chemistry and Molecular Engineering, Peking University, Beijing 100871;
b National Laboratory of Applied Organic Chemistry at Lanzhou University, Lanzhou 730000

Received Date: 19 April 1995

Fund Project: Project was supported by the National Natural Science Foundation of China, Youth Foundation of Peking University and Foundation from Zhongguancun Joint Center of Analysis.

Four analogs and three segments of the Papaver somniferum pollen peptide 2 (PSPP2) were designed and synthesized by using Merrifield solid phase peptide synthesis method.Their anti-tumour activities were determined by the tetrazolium salt MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) method and the relationship of structure-activity was discussed.
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