Citation: Wei Hua ZHOU, Yu Fen ZHAO. INTERMOLECULAR PHOSPHORYL GROUP TRANSFER FROM N-(O,O-DIISOPROPYL) PHOSPHORYL ASPARAGINE TO TRYPSIN[J]. Chinese Chemical Letters, ;1996, 7(7): 615-616. shu

INTERMOLECULAR PHOSPHORYL GROUP TRANSFER FROM N-(O,O-DIISOPROPYL) PHOSPHORYL ASPARAGINE TO TRYPSIN

Bioorganic phosphorus chemistry labortaor Tsinghua University, Beijing 100084

Received Date: 3 November 1995

Fund Project: The authors thank the financial support from the National Natural Science Foundation of China .

In Tris-HCl buffer, an intermolecular phosphoryl group transfer from N-(O, O-diisopropyl) phosphoryl asparagine (DIPPAsn) to trypsin was confirmed. The result suggested an novel way to phosphoiylate the protein without kinase participation.
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