Citation: Zheng Jie HE, Zheng Ming LI. BASE-CATALYZED PROTODESILYLATION OF (2H)-PYRI-DAZINON-5-YL SILYLMETHYL SULFIDES[J]. Chinese Chemical Letters, ;1996, 7(7): 603-604. shu

BASE-CATALYZED PROTODESILYLATION OF (2H)-PYRI-DAZINON-5-YL SILYLMETHYL SULFIDES

Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071

Received Date: 13 November 1995

Fund Project: We thank the National Science Foundation for financial support of this work and Professor Chengming Lai (Department of Chemistry, Nankai University) for some calculations about net charge.

Protodesilylation of (2H)-pyridazinon-5-yl silylmethyl sulfides 1 proceeds smoothly with cleavage of sp³ hybridized carbon-silicon bond in the presence of catalytic amount of sodium hydroxide at room temperature. The presence of aryl R on silicon atom and (2H)-pyridazinon-5-yl group on sulfur atom plays a critical role in the occurrence of this reaction.
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