Citation: Qin Zheng YANG, Jing YANG, Chang Kai ZHANG. Layered Double Hydroxide as Cordycepin Delivery Nanocarrier[J]. Chinese Chemical Letters, ;2006, 17(7): 985-987. shu

Layered Double Hydroxide as Cordycepin Delivery Nanocarrier

1.
School of Food and Bioengineering, Shandong Institute of Light Industry, Jinan 250100;
2.
State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100

Received Date: 4 January 2006

Layered double hydroxide was investigated as cordycepin delivery nanocarrier for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO₃], which was confirmed by the results of X-ray diffraction and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.
- Layered double hydroxide,
- cordycepin,
- nanohybrid,
- intercalate
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