Citation: Zhi Defu, Bai Yuchao, Zhang Lin, Zhang Shubiao. Research Progress in Magnetic Response Nano-Drug Carriers Based on Super Paramagnetic Iron Oxide[J]. Chemistry, ;2017, 80(11): 987-994, 1060. shu

Research Progress in Magnetic Response Nano-Drug Carriers Based on Super Paramagnetic Iron Oxide

Key Laboratory of Biotechnology and Bioresources Utilization, Ministry of Education, Dalian Minzu University, Dalian 116600

Corresponding author: Zhang Shubiao, zsb@dlnu.edu.cn
Received Date: 20 May 2017
Accepted Date: 11 July 2017

Figures(10)

The magnetic response nano-drug carriers based on superparamagnetic iron oxide nanoparticles (SPIONs) have been widely used in tumor diagnosis and treatment. Their stability, circulation time and sustained drug release capability are all increased by function modification of the SPIONs. They are combined with targeted ligand molecules, which can enhance their multi-targeting effect. Based on magnetism-and photo-thermal effects of SPIONs and shell materials, they can directly kill tumor cells or peel off the thermo-sensitive shell to release drugs, increase the drug concentration in the tumor site, thereby enhancing the treatment effect of tumor. Herein the progress in the magnetic response nano-drug carriers based on SPIO was reviewed.
- Nano-drug carrier,
- Super paramagnetic Fe₃O₄,
- nanoparticles,
- Controlled release,
- Stimulus response
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