Citation: Gui Rong QU, Ming Wei GENG, Su Hui HAN, Zhi Guang ZHANG, Feng XUE. Microwave-assisted Green and Efficient Synthesis of N⁶-(2-Hydroxyethyl)adenosine and its Analogues[J]. Chinese Chemical Letters, ;2006, 17(9): 1149-1151. shu

Microwave-assisted Green and Efficient Synthesis of N⁶-(2-Hydroxyethyl)adenosine and its Analogues

College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007

Received Date: 3 March 2006

Fund Project: We express our thanks to the National Natural Science Foundation of China (No. 20372018).

An efficient protocol for the synthesis of N⁶-(2-Hydroxyethyl)adenosine and its analogues through nucleophilic substitution was developed. All the reactions were completed in 10 min under microwave irradiation. Using water as solvent makes our method eco-friendly and easy to handle with.
- N⁶-(2-Hydroxyethyl)adenosine,
- nucleoside analogues,
- microwave irradiation
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