Citation: Duan Yun SI, Da Fang ZHONG, Chang Xiao LIU. Four New Isovalertatins M33, D13, D33, and D43, from the Culture Filtrate of Streptomyces luteogriseus[J]. Chinese Chemical Letters, ;2006, 17(3): 351-354. shu

Four New Isovalertatins M33, D13, D33, and D43, from the Culture Filtrate of Streptomyces luteogriseus

1.
Tianjin State Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193;
2.
Center for Drug Metabolism, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203

Received Date: 22 August 2005

Fund Project: We thank Prof. Q. Xu, Hebei University of Science and Technology, for offering the sample, WC670. This project was financially supported by China National High Technology Plan (863 Plan No. 2003AA2Z374D).

Four new aminooligosaccharides, isovalertatins M33 1, D13 2, D33 3, and D43 4, were isolated from the culture filtrate of Streptomyces luteogriseus. Their structures were established by chemical and spectroscopic evidences including ESI multistage mass spectrometry and 2-dimensional NMR techniques, and were found in full consistencies with the previous profiling results proposed by LC/ESI/MS analysis.
- Streptomyces luteogriseus,
- aminooligosaccharide,
- isovalertatins,
- metabolomics
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