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Citation:
Pi SUN, Norihiro KOBAYASHI, Junichi GOTO. Design and Synthesis of 6α-Corticosteroid Haptens and Their Bovine Serum Albumin (BSA) Conjugates[J]. Chinese Chemical Letters,
;2003, 14(3): 259-262.
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The site of attachment of protein carrier to corticosteroids has great influence on the specificity of produced antibody. In order to obtain highly specific and accurate antibodies for bioimmunoassay determination of cortisol, different tether lengths of 6α-corticosteroid haptens and their BSA conjugates were designed and synthesized.
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Keywords:
- Cortisol,
- hapten,
- monocolonal antibody,
- bioimmunoassay
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