Citation: Zong Xuan SHEN, Jian Fsng QIAN, Wen Jin QIANG, Ya Wen ZHANG. OPTICALLY ACTIVE AMINO ACIDS WITH HIGHLY BRANCHED SIDE CHAIN (I):SYNTHESIS OF D-AND L-2-AMINO-5,5-DIMETHYLHEXANOIC ACID AND 2-AMINO-6,6-DIMETHYLHEPTANOIC ACID[J]. Chinese Chemical Letters, ;1992, 3(4): 237-238. shu

OPTICALLY ACTIVE AMINO ACIDS WITH HIGHLY BRANCHED SIDE CHAIN (I):SYNTHESIS OF D-AND L-2-AMINO-5,5-DIMETHYLHEXANOIC ACID AND 2-AMINO-6,6-DIMETHYLHEPTANOIC ACID

Department of Chemistry Suzhou University Suzhou 215006

Received Date: 1 November 1991

Fund Project: This work was supported by the Natural Science Foundation of Jiangsu Province.

The title compounds were prepared by the enzymatic resolution of the corresponding N-acetylated DL-amino acids methyl esters, which were obtained from t-butyl chloride via an 8-step synthesis
1. [1]
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