Citation: Ji Cheng CHU, Dong Zhi LIU, Hong Sheng GUO, Kang ZHAO. Approach to N-Alkoxy-2-oxoindole for Mimicing SERMs Structure[J]. Chinese Chemical Letters, ;2005, 16(12): 1593-1596.
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Treatment of N-alkoxyamides with bis(trifluoroacetoxy)iodobenzene generated electron deficient nitrogen species, which readily cyclized onto aromatic ring to give N-alkoxy-2-oxoindoles. The effect of different substituent on aromatic ring to the electrophilic substitution was studied.
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