Citation: Ming Gang ZHAO, Ai You HAO, Jian LI, Xiu Li LIN. 6-O-(Hydroxypropyltrimethylammonia)-β-cyclodextrin with Low Degree of Substitution: Convenient Preparation and its Application as a Chiral Selector in Capillary Electrophoresis[J]. Chinese Chemical Letters, ;2006, 17(3): 407-410.
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A cationic cyclodextrin derivative 6-O-(hydroxypropyltrimethylammonia)-β-cyclodextrin (GTA-β-CD) with low degree of substitution was prepared through a convenient method in solid phase. The product could be used as a valuable chiral selector in the capillary electrophoresis (CE) separation of some acidic drug enantiomers such as naproxen, ofloxacin, ibuprofen and warfarin.
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