Citation: Zai Guo LI, Run Qui HUANG, Hui Ying LI. An Efficient Synthesis of Heterocyclic Substituted Ureidoalkylphosphonates[J]. Chinese Chemical Letters, ;1998, 9(3): 251-253. shu

An Efficient Synthesis of Heterocyclic Substituted Ureidoalkylphosphonates

Institute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071

Received Date: 18 November 1997

A convenient synthesis of various heterocyclic substituted ureidoalkylphosphonic acid diphenyl esters 3 is reported in this paper. a-Aminoalkylphosphonic acid diphenyl esters 1 reacted with triphosgene, and then treated with heterocyclic amines gave 3. Small amount of symmetric urylenediphosphonate 4 are isolated as side products.
- ureidoalkylphosphonic acid diphenyl ester,
- triphosgene,
- heterocyclic amine,
- α-isocyanatoalkylphosphonic acid diphenyl ester
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