Citation: Jian Ya LING, Jian Qun LIN, Guo Ying ZHANG, Chang Kai ZHANG. Study on the Binding Effect between Cordycepin and Calf Thymus DNA by Circular Dichroism[J]. Chinese Chemical Letters, ;2006, 17(10): 1351-1352. shu

Study on the Binding Effect between Cordycepin and Calf Thymus DNA by Circular Dichroism

1.
State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100;
2.
Traditional Chinese Medicine of Shandong University, Jinan 250014;
3.
School of Environmental Science and Engineering, Shandong University, Jinan 250100

Received Date: 10 May 2006

Binding of cordycepin to the double helical DNA with a high affinity was investigated by CD spectra in this paper. The results proved that uncoiling, unbinding and denaturation of DNA proceeded continuously upon the increase of the concentration of cordycepin.
- Cordycepin,
- DNA-binding,
- CT-DNA,
- conformation,
- spectroscopic technique
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