Citation: Min Min YANG, Jin Qi ZHANG, Zhen SHEN. A New One-Pot Synthesis of Macroheterocycles Using Mannich Reaction[J]. Chinese Chemical Letters, ;1997, 8(10): 845-846. shu

A New One-Pot Synthesis of Macroheterocycles Using Mannich Reaction

Department of Chemistry, Nanjing University, Nanjing 210093

Received Date: 7 July 1997

Fund Project: This project was financially supported by 863 key research project from the State Science and Technology Commission.

Three N,N'-heterylmethyl derivates of diaza-18-crown-6(I) are readily prepared by the reaction of (I) with paraformaldehyde and heterocyclic compounds in dry benzene.
1. [1]
  Lei Zhang , Kaimin Chen , Luchang Li , Xiu Wei , Xianxin Cai , Yaohui Yu , Yixian Yang , Renping Cao , Fenghua Wei , Bang Lan , Yanhua Li , Xiaohu Luo , Hui Liang , Deshuai Zhen . One-pot synthesis of Ni–Co nanoparticles@Ni_0.19Co_0.26P nanowires core/shell arrays on Ni foam for efficient hydrogen evolution reaction at all pH values. Chinese Chemical Letters, 2026, 37(6): 111002-. doi: 10.1016/j.cclet.2025.111002
2. [2]
  Min Fu , Ruihan Wang , Wenqiang Liu , Sen Zhou , Chunhong Zhong , Yaohao Li , Pan He , Xin Li , Shiying Shang , Zhongping Tan . Improved one-pot protein synthesis enabled by a more precise assessment of peptide arylthioester reactivity. Chinese Chemical Letters, 2025, 36(7): 110542-. doi: 10.1016/j.cclet.2024.110542
3. [3]
  Jun-Gang Wang , Bing-Yi Zhou , Yao-Luo Hu , Yong-Dong Du , Rong-He Wu , Chun-Yan Wu , Wen-Chao Yang , An-Xin Wu . Atom-swapping skeletal editing of benzo[c]oxepines for the construction of 2-benzodiazepines via a continuous manufacturing one-pot synthesis. Chinese Chemical Letters, 2026, 37(4): 111200-. doi: 10.1016/j.cclet.2025.111200
4. [4]
  Yu Pang , Min Wang , Ning-Hua Yang , Min Xue , Yong Yang . One-pot synthesis of a giant twisted double-layer chiral macrocycle via [4 + 8] imine condensation and its X-ray structure. Chinese Chemical Letters, 2024, 35(10): 109575-. doi: 10.1016/j.cclet.2024.109575
5. [5]
  Chun-Ying Xu , Xiao-Lin Luan , Yuan-Yuan Cui , Cheng-Xiong Yang . One-pot in situ doping synthesis of phenylboronic acid-functionalized magnetic-cyclodextrin microporous organic network for specific enrichment and detection of sulfonylurea herbicides. Chinese Chemical Letters, 2025, 36(9): 110937-. doi: 10.1016/j.cclet.2025.110937
6. [6]
  Ren Shen , Yanmei Fang , Chunxiao Yang , Quande Wei , Pui-In Mak , Rui P. Martins , Yanwei Jia . UV-assisted ratiometric fluorescence sensor for one-pot visual detection of Salmonella. Chinese Chemical Letters, 2025, 36(4): 110143-. doi: 10.1016/j.cclet.2024.110143
7. [7]
  Mengxing Liu , Jing Liu , Hongxing Zhang , Jianan Tao , Peiwen Fan , Xin Lv , Wei Guo . One-pot accessing of meso–aryl heptamethine indocyanine NIR fluorophores and potential application in developing dye-antibody conjugate for imaging tumor. Chinese Chemical Letters, 2025, 36(4): 109994-. doi: 10.1016/j.cclet.2024.109994
8. [8]
  Yufeng Gan , Deqian Zeng , Shunyan Ning , Ningchao Zheng , Xinpeng Wang , Yuezhou Wei , Jizhou Jiang . Synergistic H₂ production and tetracycline degradation: Unveiling the mechanism of a one-pot synthesized CeO₂/CdS photocatalyst. Chinese Chemical Letters, 2026, 37(5): 111717-. doi: 10.1016/j.cclet.2025.111717
9. [9]
  Xu-Hui Yue , Xiang-Wen Zhang , Hui-Min He , Lei Qiao , Zhong-Ming Sun . Synthesis, chemical bonding and reactivity of new medium-sized polyarsenides. Chinese Chemical Letters, 2024, 35(7): 108907-. doi: 10.1016/j.cclet.2023.108907
10. [10]
  Yue Pan , Jing Ren , Yifan Sun , Luying Lu , Jia Gao , Liping Chen , Shancheng Yan , Zhiyang Li . Harnessing chirality: A new dawn in inorganic nanomaterial synthesis and biomedical applications. Chinese Chemical Letters, 2026, 37(4): 110791-. doi: 10.1016/j.cclet.2024.110791
11. [11]
  Yidian Mo , Ao Sun , Hang Dong , Zhongtang Li , Zhongjun Li . Synthesis of α-d-fructofuranosides and difructose dianhydride Ⅳ using glycosyl fluorides as donors. Chinese Chemical Letters, 2026, 37(7): 111922-. doi: 10.1016/j.cclet.2025.111922
12. [12]
  Dong-Sheng Deng , Su-Qin Tang , Yong-Tu Yuan , Ding-Xiong Xie , Zhi-Yuan Zhu , Yue-Mei Huang , Yun-Lin Liu . C-F insertion reaction sheds new light on the construction of fluorinated compounds. Chinese Chemical Letters, 2024, 35(8): 109417-. doi: 10.1016/j.cclet.2023.109417
13. [13]
  Quanxing Mao , Zhengliang Wang , Zhinan Hu , Ziqi Yang , Hui Li , Yali Yao , Zijun Yong , Tianyi Ma . Facial detection of formaldehyde by using acidichromic carbon dots and the reaction between formaldehyde and ammonium chloride. Chinese Chemical Letters, 2025, 36(7): 110499-. doi: 10.1016/j.cclet.2024.110499
14. [14]
  Pin Cui , Ying Tang , Jie Yu , Zhen Yang , Shouhua Yang , Boqin Li , Gang Wang , Huan Pang , Feng Yu . Bimetallic ZnFe–NC prepared using microchannel reactor for oxygen reduction reaction and mechanism research. Chinese Chemical Letters, 2025, 36(9): 110303-. doi: 10.1016/j.cclet.2024.110303
15. [15]
  Dan PENG , Hao WANG , Yanyan WANG , Hongpeng YOU , Wuping LIAO . Synthesis and fluorescent properties of a one-dimensional Tb-calixarene complex as a luminescent thermometer material. Chinese Journal of Inorganic Chemistry, 2025, 41(9): 1859-1866. doi: 10.11862/CJIC.20250128
16. [16]
  Xinyu Gu , Jun Yu , Huiyu Sun , Nannan Zhang , Zhengying Wu , Yukou Du . One-step synthesis of trimetallic PdCuNi porous nanoflowers for enhanced alcohol oxidation. Chinese Chemical Letters, 2026, 37(1): 111756-. doi: 10.1016/j.cclet.2025.111756
17. [17]
  Yuqi Zhu , Suhua Chen , Jianping Zou , Bo Li , Wei Ren , Gaoxia Zhang , Jiajie Wang , Xinyu Liu , Qianhui Li , Huiying Zhang , Fanying Xia . Single-atom catalysts partner with defects to open a new chapter in catalysis: Synthesis, performances, and mechanisms. Chinese Chemical Letters, 2026, 37(7): 112192-. doi: 10.1016/j.cclet.2025.112192
18. [18]
  Kebo Xie , Qian Zhang , Fei Ye , Jungui Dai . A multi-enzymatic cascade reaction for the synthesis of bioactive C-oligosaccharides. Chinese Chemical Letters, 2024, 35(6): 109028-. doi: 10.1016/j.cclet.2023.109028
19. [19]
  Liming Li , Yanchang Liu , Peng Kang , Donghui Feng , Yuguang Zhang , Hangxing Ren , Jianrong Zeng , He Zhu , Qiang Li , Xiaoya Cui . Scalable and rapid liquid synthesis of PtNi electrocatalyst for hydrogen evolution reaction. Chinese Chemical Letters, 2026, 37(2): 112022-. doi: 10.1016/j.cclet.2025.112022
20. [20]
  Meihui Cai , Yi Huang , Xingxing Ma , Qiuling Song . Exploring the Mysteries of the Petasis-Boronic Acid-Mannich Reaction. University Chemistry, 2025, 40(11): 184-190. doi: 10.12461/PKU.DXHX202412054

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(1523)
HTML views(27)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return