Citation: Wei Hua HAN, Hao Ran LI. A Novel Asymmetric Synthesis of (-)-cis-1, 3-Dibenzylhexahydrofuro [3, 4-d]imidazole-2,4-dione[J]. Chinese Chemical Letters, ;2005, 16(1): 15-16. shu

A Novel Asymmetric Synthesis of (-)-cis-1, 3-Dibenzylhexahydrofuro [3, 4-d]imidazole-2,4-dione

Wei Hua HAN ,
Hao Ran LI

Department of Chemistry, Zhejiang University, Hangzhou 310027

Received Date: 18 November 2003

Fund Project: This work was supported by the Natural Science Fundation of Zhejiang Province of China (No:RC01051).

(-)-cis-1, 3-Dibenzyl-hexahydrofuro[3, 4-d]imidazole-2, 4-dione was prepared by a new synthesis method from meso dicarboxylic acid and dehydroabietylamine by asymmetric reduction in good yield with up to 91.6% e.e. value.
- Synthesis,
- lactone,
- dehydroabietylamine,
- reduction,
- asymmetric.
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