Citation: Jun Gui DAI, Meng ZHANG, Min YE, Wei Hua ZHU, Ji Yu GUO, Xiao Tian LIANG. Biotransformation of 14-Deacetoxy-13-oxo sinenxan A by Ginkgo Cell Cultures[J]. Chinese Chemical Letters, ;2003, 14(8): 804-806. shu

Biotransformation of 14-Deacetoxy-13-oxo sinenxan A by Ginkgo Cell Cultures

Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100050

Received Date: 5 September 2002

Fund Project: This work is supported by the National Natural Science Foundation of China (to Jungui Dai, No.30100230).

14-Deacetoxy-13-oxo sinenxan A (1) was converted to 9α-hydroxy-13-oxo-2α, 5α, 10β-triacetoxy-4(20),11-taxadiene (2) and 10β-hydroxy-13-oxo-2α,5α,9α-triacetoxy-4(20), 11-taxadiene (3) by Ginkgo cell suspension cultures in 45% and 15% yields, respectively.
- Biotransformation,
- taxane,
- cell suspension cultures,
- Ginkgo biloba L
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