Citation: Ping WU, Xi Mei CAI, Rong YAO, Chao Guo YAN. Microwave Irradiated Reactions of N-Phenacylpyridinium Chloride with Aromatic Aldehydes and Ketones[J]. Chinese Chemical Letters, ;2006, 17(7): 867-870. shu

Microwave Irradiated Reactions of N-Phenacylpyridinium Chloride with Aromatic Aldehydes and Ketones

Ping WU ^1, ,
Xi Mei CAI ² ,
Rong YAO ² ,
Chao Guo YAN ²

1.
Yangzhou Polytechnic College, Yangzhou 225009;
2.
College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002

Received Date: 19 December 2005

In the system of ammonium acetate and acetic acid and under microwave irradiation,N-phenacylpyridinium chloride 1 reacted with chalcone 2 to give 2,4,6-triarylpyrididnes 3a-g in high yields. 3a-g can also be prepared from one-pot reaction of 1 with aromatic aldehydes 4 and substituted acetophenones 5. Under the same conditions 1 can also react with pyridinecar boxaldehyde 6a-c and acetophenone to yield bipyridine derivatives 7a-c. 1 reacted with aromatic aldehyde and cyclohexanone 6 to yield 2,4-diaryltetrahydroquinolines 8a-d. At last 1 reacted with aromatic aldehydes to give 2,4,6-triarylpyrimidine 9a-i. The structure of the products was characterized with ¹H NMR and IR and mass spectroscopy.
- Microwave irradiation,
- chalcone,
- condensation,
- pyridine,
- pyrimidine
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