Citation: Cai Lian SU, Rong Ji DAI, Bin TONG, Yu Lin DENG. Preparation and Chiral Selectivity of BSA-Modified Ceramic Membrane[J]. Chinese Chemical Letters, ;2006, 17(5): 649-652. shu

Preparation and Chiral Selectivity of BSA-Modified Ceramic Membrane

1.
School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081;
2.
School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081

Received Date: 19 September 2005

Fund Project: This work is supported by the National Natural Science Foundation of China (No. 20275004).

An affinity-transport system, containing porous ceramic membranes bound with bovine serum albumin (BSA) was used for chiral separation of racemic tryptophan. The preparation of BSA modified ceramic membrane included three steps. Firstly, the membrane was modified with amino group using silanization with an amino silane. Secondly, the amino group modified membrane was bound with aldehyde group using gluteraldehyde. Finally, BSA was covalently bound on the surface of the ceramic membrane. Efficient separation of racemic tryptophan was carried out by performing permeation cell experiments, with BSA modified, porous ceramic membranes.
- Ceramic membrane,
- chiral separation,
- bovine serum albumin
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