Citation: Pei Ji ZHAO, Yue Mao SHEN. Neo-lignans in the Seed Crusts of Trewia nudiflora[J]. Chinese Chemical Letters, ;2004, 15(8): 921-924. shu

Neo-lignans in the Seed Crusts of Trewia nudiflora

The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204

Received Date: 14 July 2003

Fund Project: This work was partially supported by the Ministry of Science and Technology grant 2001-51, the National Natural Science Foundation of China (30070007), Chinese Academy of Sciences (KSCX2-SW-313) and Natural Science Foundation of Yunnan Province (99B0017G). The authors are grateful to Mr. Y. N. He and Ms. H. L. Liang in the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring NMR and MS data, respectively.

Four new neo-lignans were isolated from the chloroform portion of 70% ethanol extract of the seed crusts of Trewia nudiflora L., and were determined to be 9'-methoxy-7'-en-3',8:4',7-di-epoxyneolignan-3,4,9-triol 1, 9'-methoxy-7'-en-3',7:4',8-diepoxyneolignan-3,4,9-triol 2, 9'-ethoxy-7'-en-3',8:4',7-diepoxyneolignan-3,4,9-triol 3, 9'-butoxy-7'-en-3',8:4',7-diepoxy-neolignan-3,4,9-triol 4, respectively, on the basis of spectral data.The antimicrobial bioassays showed that 4 had evident inhibitory activity against Mycobacterium tuberculosis.
- Trewia nudiflora,
- neo-lignans,
- antibacterial activity
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