Citation: Shi Lei LIU, Xiu Bao DU, Jing Lin KONG. New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai[J]. Chinese Chemical Letters, ;2006, 17(1): 41-44. shu

New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai

Research Institute of Chemical Defense, Beijing 102205

Received Date: 8 May 2005

Three viscotoxins have been isolated from Chinese mistletoe, Viscum coloratum (Kom.) Nakai. The primary structures were determined unambiguously by the combination of Edman degradation, endoproteinase Elu-c digestion, and Q-TOF mass spectrometry. One was identified as viscotoxin C1, which was for the first time isolated from Chinese mistletoe. The other two were new polypeptides, named as viscotoxin B5 and viscotoxin B8. Pharmacological studies showed that the polypeptides exhibit distinct cytotoxicity to human cancer cells.
- Viscum coloratum,
- mistletoe,
- isolation,
- primary structure,
- viscotoxin
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