Citation: Li Yuan MOU, Zi Yun LIN, Li Ya ZHU, Xiao Tian LIANG. A New Investigation of Mannich Reaction[J]. Chinese Chemical Letters, ;2001, 12(6): 471-474. shu

A New Investigation of Mannich Reaction

1.
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050;
2.
Center for Biophysical Science and Engineering University of Alabama at Birmingham 90114 th street South, Birmingham, AL 35294

Received Date: 25 September 2000

Fund Project: This work was supported by the National Natural Science Foundation of China.

During the synthesis of the derivatives of styryl ketonic Mannich bases, a side-product IM,other than the normal Mannich base MA, is obtained. Mannich reaction is further studied and the formation mechanism of product IM is postulated and discussed on the basis of deuterium labelling.
- Mannich reaction,
- side-product,
- styryl ketonic Mannich bases,
- mechanism.
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