Citation: Xian Zhi DONG, Hui Bi XU, Kai Xun HUANG, Qiong LIU. Isolation and Characterization of an Antinicrobial Polypeptide from Loach[J]. Chinese Chemical Letters, ;2003, 14(1): 54-57. shu

Isolation and Characterization of an Antinicrobial Polypeptide from Loach

Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074

Received Date: 8 April 2002

A novel antimicrobial polypeptidc was isolated and charaeterized from loach, Misgurmis anguillieaudatus, The polypcptide, named MAPP, is a single-chain polypcptide with Mw about 9,800 Dalton and p1 about 4.78;the N-tag ofMAPP was CFGWN. MAPP showed good inhibition against various bacteria including Bacillus subtilis, Eseherichia coli and Staphylococcus aurens. MAPP could be used as a lead compound in antibiotics drug discovery.
- Misgurnus anguillicaudatus,
- isolation,
- characterization
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