Citation: Liu Qinghua, Yang Ping, Gao Chuanzhu, Yang Bo, Qian Yunxu. Research Progress in Gold Nanoparticle-Based Delivery Systems of Antitumor Platinum Drugs[J]. Chemistry, ;2017, 80(11): 995-1001. shu

Research Progress in Gold Nanoparticle-Based Delivery Systems of Antitumor Platinum Drugs

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500

Corresponding author: Gao Chuanzhu, gczasd@163.com
Received Date: 12 April 2017
Accepted Date: 13 July 2017

Figures(9)

Platinum drugs have become one of the most widely used anticancer drugs due to their unique mechanisms of action. However, the clinical use of platinum anticancer drugs were limited by serious side effects, drug resistance and other issues. In order to overcome the deficiencies of platinum anticancer drugs, improve the bioavailability of platinum anticancer drugs and reduce their side effects, targeted drug delivery system to change the in vivo transmission method of the platinum drugs has been widely concerned. Among of them, the platinum drugs-gold nanoparticles delivery system has significantly caused the attention of researchers for its high loading capacity, easy modification, cancer cells EPR effect and non-immunogenicity, etc. In this paper, the research progress in nanogold delivery systems for platinum-based antitumor drugs in recent ten years were introduced.
- Platinum drugs,
- Gold nanoparticles,
- Drug loading system
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