Citation: Zhou Mingdong, Du Haiwu, Gong Xinyu, Sun Jing. Progress in the Syntheses of Coumarin Derivatives through Tandem Radical Addition/Cyclization[J]. Chemistry, ;2019, 82(9): 789-795. shu

Progress in the Syntheses of Coumarin Derivatives through Tandem Radical Addition/Cyclization

School of Chemistry and Materials Science, Liaoning Shihua University, Fushun 113001

Received Date: 29 May 2019
Accepted Date: 28 June 2019

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Coumarin and its derivatives are a key class of heterocyclic lactone compounds, which are widely applied in the fields of organic synthesis, pharmaceutics, fluorescent materials, and so on. The development of a novel simple and efficient synthetic strategy of coumarins has been paid much attention. Recently, the tandem radical addition/cyclization of alkynoate with radical precursor afforded a simple, green and efficient method to synthesize coumarins. In this review, the recent progress in the synthesis of coumarins through tandem radical addition/cyclization is summarized.
- Coumarin,
- Alkynoate,
- Radical cyclization,
- Functionalization
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