Citation: Liang XU, Guang Rong ZHENG, Min XIA, Jun Chao CAI. Synthesis of 2-methoxy-6-oxo-1,4,2-diazaphosphorinane-2-oxide, A New Potential Antitumor Phosphorus Heterocycle Compound[J]. Chinese Chemical Letters, ;2000, 11(8): 665-666. shu

Synthesis of 2-methoxy-6-oxo-1,4,2-diazaphosphorinane-2-oxide, A New Potential Antitumor Phosphorus Heterocycle Compound

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031

Received Date: 27 January 2000

2-methoxy-6-oxo-1,4,2-diazaphosphorinane-2-oxide 8, phosphorus counterpart of 2,6-dioxopiperazine, was synthesized as antitumor agent. The new phosphorus heterocycle compound 8 is the key intermediate in the synthesis of phosphorus counterpart of bisdioxopiperazine.
- Antitumor activity,
- phosphorus heterocycle compound,
- 2,6-dioxopiperazine
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