Citation: Xing Shan TIAN, Shuang Da XIE, Xue Bing JIANG, Xiao Mao ZHOU, Li Mei YANG, Ding Jun XIAO. Bandunamide, a Novel Cyclopeptide from the Streptomyces Griseovariabilis bandungensis[J]. Chinese Chemical Letters, ;2003, 14(12): 1255-1258. shu

Bandunamide, a Novel Cyclopeptide from the Streptomyces Griseovariabilis bandungensis

1.
Guangdong Academy of Agricultural Sciences, Guangzhou 510640;
2.
Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou 510650

Received Date: 18 November 2002

Fund Project: This work was supported by NNSFC Grant 39870903 and Guangdong Provincial Scientific Grant 980726.

A new cyclic octapeptide, bandunamide, was isolated from the acetone extracts of streptomyces griseovariabilis bandungensis. This cyclic octapeptide exhibits strong antimicrobial activity against Phytophthora drechsleri (IC₅₀=15 ng/mL), Colletotrchum higginsiannum (IC₅₀=15.6 ng/mL), Piricularia oxyzae (IC₅₀=0.2 μg/mL), and Fusarium oxysporum f. Sp. (IC₅₀=100 μg/mL). The structure elucidation of bandunamide is herein reported.
- Streptomyces,
- Griseovariabilis bandungensis,
- Bandunamide,
- structure elucidation,
- anti-fungus
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