Citation: Da Li YIN, Ji Yu GUO, Xiao Tian LIANG. A Convergent Route for the Synthesis of AF-5[J]. Chinese Chemical Letters, ;2003, 14(7): 670-672. shu

A Convergent Route for the Synthesis of AF-5

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050

Received Date: 26 November 2002

Fund Project: The authors gratefully acknowledge financial support from the National Natural Science Foundation of China (No.39370809) and National New Drug Foundation (No.92-08-N).

AF-5 was synthesized through a convergent method. The key step was the Robinson annulation using a key intermediate pentyl vinyl ketone.
- AF-5,
- synthesis,
- Robinson annulation
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