Citation: Qiao-Ling Liu, Meng Fan, Wei Bian, Shao-Min Shuang, Chuan Dong. Synthesis of a new ratiometric emission Ca²⁺ indicator for in vivo bioimaging[J]. Chinese Chemical Letters, ;2013, 24(2): 156-158. shu

Synthesis of a new ratiometric emission Ca²⁺ indicator for in vivo bioimaging

1.
a Research Center of Environmental Science and Engineering, Shanxi University, Taiyuan 030006, China;
2.
b Department of Chemistry, Taiyuan Normal University, Taiyuan 030031, China

Corresponding author: Chuan Dong,
Received Date: 4 November 2012
Available Online: 5 December 2012
Fund Project:

A novel fluorescent calcium indicator with a 490/582 nm ratiometric emission has been designed and synthesized. The indicator exhibits a highly selective ratiometric emission response to Ca²⁺ over other metal cations and a large Stokes shift of 202 nm. Moreover, its practical cell imaging capability for intracellular Ca²⁺ in the resting-and dynamic-state has been demonstrated in human umbilical vein endothelial cells using a confocal laser scanning microscope.
- Ca²⁺ indicator,
- Ratiometric emission,
- Bioimaging
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Synthesis of a new ratiometric emission Ca2+ indicator for in vivo bioimaging

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通讯作者: 陈斌, bchen63@163.com

Synthesis of a new ratiometric emission Ca²⁺ indicator for in vivo bioimaging