Citation: Shuang Zhang, Ji-Ming Yan, An-Jun Qin, Jing-Zhi Sun, Ben-Zhong Tang. The specific detection of Cu(Ⅱ) using an AIE-active alanine ester[J]. Chinese Chemical Letters, ;2013, 24(8): 668-672. shu

The specific detection of Cu(Ⅱ) using an AIE-active alanine ester

1.
a MoE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China;
2.
b Department of Chemistry, Institute of Molecular Functional Materials, the Institute for Advanced Study (IAS), The Hong Kong University of Science & Technology, Hong Kong, China

Corresponding author: Jing-Zhi Sun, Ben-Zhong Tang,
Received Date: 25 February 2013
Available Online: 17 April 2013

Cu(Ⅱ) detection is important because it plays crucial role in several biological processes and ecological systems. Fluorescent techniques have attracted more and more attention in Cu(Ⅱ) detection. In this report, we contribute a novel strategy to use fluorescence spectroscopy for Cu(Ⅱ) specific detection. The specificity relies on the fact that, of the many metal cations, only Cu(Ⅱ) can catalyze the hydrolyzation of a-amino acid ester. The novelty originates from the unique aggregation-induced emission (AIE) property of the fluorescent label. We designed a model a-amino acid ester (TPE-Ala) constructed with alanine and tetraphenylethene-functionalizedmethanol (TPE-methanol). In comparison with the precursor TPE-Ala, TPE-methanol has lower solubility and is easy to form aggregates in water, thereby displaying a higher fluorescent response. Thus, the Cu(Ⅱ) catalyzed hydrolyzation can be monitored by recording the fluorescence enhancement and fluorescent detection Cu(Ⅱ) is rationally achieved.
- Aggregation-induced emission,
- Fluorescence enhancement,
- Cu(Ⅱ) catalyzed
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